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The longest running TV spinoff of the Marvel Cinematic Universe, and the first of the TV branch of the MCU. Agents of S.H.I.E.L.D. starred Phil Coulson, having being brought back to life after his death in The Avengers. The newly-revived Coulson leads a team of S.H.I.E.L.D., most of them created for the show (the only notable exception being Mockingbird and Quake).

Due to being, to some extent, more connected to the movies than other MCU shows, the events of Captain America: The Winter Soldier had the show scrambling to justify its existence.

The show was meant to end in its fifth season in 2018, having a reference to Thanos' second attack on New York in Avengers: Infinity War only for the show to continue for two more seasons, leaving the fallout of the Snap conspicuously unaddressed.

After seven years and seven seasons, the show finally came to an end on August 12 2020.

Tropes used in Agents of S.H.I.E.L.D. include:
  • Adaptation Species Change: Several characters are now Inhumans. The notable exception is Donnie Gill who's now an Enhanced Human rather than an Inhuman.
  • Arc Words: "Tahiti, it's a magical place".
  • Badass Normal: Most agents, with Quake being the exception.
  • Back From the Dead: Phil Coulson, thanks to a good injection of Kree blood.
  • Composite Character All Along: Provides the trope image. Glenn Talbot becomes the MCU version of Graviton.
  • Continuity Snarl: Thanks to the show mentioning that Season 5 took place at the same time as Infinity War, it is impossible to reconcile anything post-Season 6 with the larger MCU.
  • Decomposite Character: Though Franklin Hall appeared in Season 1, it's Glenn Talbot who becomes Graviton.
  • Mandshake: In "The Totally Excellent Adventures of Mack and the D".
  • Red Skies Crossover:
    • This trope is how the show connects to the movies.
    • Microchip is mentioned in this show before becoming a major character in The Punisher.
    • The Inhuman ruins from this show are featured in Inhumans.
  • Required Spinoff Crossover: Nick Fury, Maria Hill and Sif appear in episodes of the show. Flashbacks show Peggy Carter and the Howling Commandoes.
  • Rogues Gallery Transplant: Many villains in the show weren't enemies of SHIELD specifically in the comics.