He blows stuff up AND kidnaps puppies!
Jonny Quest has faced his fair share of particularly heinous main antagonists across differet incarnations.
The New Adventures[]
- The wicked Deprave is from a nation bordering two countries formerly in peace talks. Kidnapping Hadji's kindly mentor, Deprave subjects him to painful mental control to use his powers to sabotage the peace talks, with her intention being to force both nations to go to war and completely obliterate one another so she may preside over attempts to pick up the pieces.
Jonny's Golden Quest & Jonny Quest vs. the Cyber Insects[]
- Dr. Zin is the Arch Enemy of the Quest family, having killed Jonny's mother in Golden Quest. Returning in Cyber Insects with an army of genetically modified insects to invade Earth, Zin utilizes a stealth satellite to cause vast parts of the world to freeze or be subjected to horrible storms, causing starvation with potentially millions threatened. A truly horrible boss, Zin is also fond of horrifically killing his minions for petty reasons, having one fed to his "mosquitoids" for entirely pragmatic advice and another frozen to death for Dr. Quest's escape despite never being in charge of watching him. Plotting to conquer the Earth, Zin stops at nothing to ensure his total domination, likening it to "breaking a few eggs" for an omelette.
Jonny Quest: The Real Adventures[]
- "Rock of Rages" & "General Winter": General Vostok is a frozen-cold ex-KGB terrorist who yearns for a world "free of having to make decisions." Vostok introduces himself icily murdering two treasure hunters to procure a destructive golem with which he attempts to assassinate the President of the Czech Republic, and later attempts to create a flash-freezing superweapon he first tests by flash-freezing a base full of soldiers to death. Vostok strong-arms a scientist friend of Dr. Benton Quest into perfecting the device, and when the scientist chafes, Vostok shoots him dead in front of Quest to hurt him. Vostok appears one last time in the comics where he attempts to convert a nuclear reactor into the world's most potent nuclear weapon, one he spitefully attempts to set off when foiled heedless of all the lives—all of his own men included—he'll waste in the process.
- James Compton, from "AMOK", is a former special forces operative thought killed-in-action but now working as a freelance mercenary for whoever can hire him. Paid by a private party to investigate a hindrance to the drug trade in Borneo, Compton assumes the identity of "Mitchell Stramm" after his party is seemingly wiped out by the native Amok monster, winning his way into the Quest's family's good graces and finding the village that's been disrupting the drug trade. Smugly betraying the Quests at this point, Compton opts to simply massacre every last native man, woman, and child in the village to remove them as an obstacle, gloating that his employers will pay him handsomely for each head he brings back to them, attached to the bodies or not.
- The succubus/vampire known as Elise Lenior from "Eclipse." Appearing as an innocent young woman on the run from evil men, Elise maintained her youth and beauty by draining the life from beautiful, innocent women. The man hunting her had lost his sister to her years past. Elise murdered the men who tried to tail her, and later mind controlled Hadji into her slave to bring Jessie to her for her food source. When her right-hand man protested about Elise trying to replace him with Hadji, Elise declared he was right and sucked the life from him as well. When her deadline of an eclipse was approaching, Elise abandoned all pretense of charm and subtlety and assumed her monstrous true form to kill everyone and drain Jessie's life.
- Von Romme from "Nuclear Netherworld" is a Corrupt Corporate Executive extraordinaire who built his company over a uranium mine. Von Romme abuses his own minions; looks the other way when his uranium irradiates the water supply of the local Hopi population; and when a local farmer tries to expose him, Von Romme has him murdered and his death made to look like an accident. Von Romme's true evil comes to light when it's revealed he's selling the uranium to terrorists for them to make nuclear weapons with, as Von Romme stays ambivalent as to whomever gets nuked so long as his bank stays intact.
- Dja'Lang Mukharno, from "Diamonds and Jade", is a puppeteer and brother of Kumar who exploits his people's old traditions for personal benefit. Coaxing his weak-willed brother into routinely selling off a rare gem to greedy buyers, Dja'Lang summons a shadow demon to brutally kill the buyers and anyone else in the premises to keep the money and the gem. Dja'Lang attempts to kill the Quest family and their friend Jade alongside the cops in the area when Jade sets Kumar up, and when Kumar loses the gem to the Quest family, Dja'Lang turns the shadow beast on him with full intent to murder him for his failure, laughing that he should have killed him years ago.