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[Doc Brown and Marty are hijacking a train]

Doc: Reach!

Engineer: Is this a holdup?

Doc: It's...a science experiment!
Doc Brown, Back to The Future III
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There is no such thing as "Good Knowledge" or "Evil Knowledge". There is only Knowledge. Morality is when you decide not to use it.
Anonymous
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This was when science didn't have to have any specific purpose.
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What a fine day... for Science!
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David Rossi: They were human beings.

Mason Turner: They were transients and drug users and prostitutes. They were useless to society. I gave them the chance to be part of a cure. To be of use. That's science.
Criminal Minds, "To Hell..."/"...and Back"
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Snake: Let's change the subject. Did you invent Metal Gear?

Otacon: Yes, as a weapon of love and peace! It fires flowers and rainbows and turns incoming warheads into puppies and butterflies!

Snake: Sounds about right, if by "flowers and rainbows" you mean "nuclear missiles."

Otacon: Oh no, how could it be that I've invented a weapon specifically for the purpose of filling everyone with warm fuzzy joy and never once realized that it was better suited for dropping nuclear weapons on faraway nations!?

Snake: My guess would be it's because you're a big idiot.
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When science is on the march, nothing can stand in its way!
Paul Bartel, Amazon Women on the Moon
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Science never sacrifices itself. It is always murderous.
Jean Baudrillard, Simulacra and Simulation
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I will date the girl from Venus

Flowers die and so will I

Yes, I will kiss the girl from Venus

For Science!
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That's why scientists have written papers with boring titles such as "Will Relativistic Heavy-ion Colliders Destroy Our Planet?", the rebuttals to which were basically, "Let's turn them on and find out!"
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Like any corporation involved in dangerous research, it all boils down to risk versus reward for the Umbrella Corporation. In this case, the risk is zombies, and the reward is zombies.
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Once ze rockets are up, who cares vere zey come down?

"Zat's not my department," says Wernher von Braun.
Tom Lehrer, "Wernher Von Braun"
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Oh, Pyriss! Though minds concerned with the follies of human existence might see your life as a tragedy, I must maintain my scientific detachment, and see your agonized existence for what it is: My Rosetta stone! Your genetic structure will finally unlock all the secrets of the Devouring Earth to me! The world has no idea what waits for it, but you, you shall be here to see the dawning of a new day for SCIENCE!
Werner Von Grün, City of Heroes
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You might as well have said, "Hey, we just made cancer airborne and contagious. You're welcome! We're science! We're all about 'coulda', not 'shoulda'."
Patton Oswalt, on a 63 year old woman giving birth, Werewolves and Lollipops
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Don't worry, I'm doing it FOR SCIENCE! and that makes everything okay.

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This is the best data, ever!
Grant of Myth Busters, doing bungee jumping
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Lisa Simpson: Mr. Tatum, do you mind if I swab you with this damp rag?

Drederick Tatum: No, not at all. Swab away. ... Whoa, whoa, nobody mentioned a beaker.

Lisa Simpson: Please? It's for science.

Drederick Tatum: Oh, for science. In that case, proceed.
The Simpsons, "Bye Bye Nerdie"
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Sally Impossible: What could possibly be more important than your son?

Richard Impossible: Sssssssscience?
The Venture Brothers, "Twenty Years to Midnight"
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Aperture Science

We do what we must

because we can.

For the good of all of us.

Except the ones who are dead.

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Empirical data's your only man, when formulating a research plan.

A soldier's death is never in vain if it makes the formula more plain.

A few dozen make a better case for refining that third decimal place.

They call me Zombie because I don't sleep, as I slowly struggle to climb this heap,

of corpses, data points, and trials, but from the top - I'll see for miles!
Zombie's forum signature
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The fact that it actually seemed a credible threat nonetheless proved no deterrent to Merrick's burning experimental quest... He was unsteady with trepidation, shivering in the chamber's humid, blasting heat, more apprehensive on this occasion than the first time he had encountered one of these things. Was this because he knew what he was doing was wrong? He couldn't afford to think about that. He had to proceed. There would be no second chances at this, and he had to know.
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Scientists are like children told not to look in a particular room... Once their minds are set upon it, nothing will mean so much to them as their desire to uncover whatever is locked to them. No matter how disastrous the possible consequences, they regard their work as paramount, as though the pursuit of science constitutes its own moral imperative... Scientists pride themselves on objectivity, but they cannot be trusted to be objective when it comes to the morality of their own conduct.
Cardinal Tullian, Pandaemonium
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I just had to see if I could. I knew my life would be ruined if I did do it and if I didn't. So I chose science.
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Howard: And as long as we're talking about betraying our friends, how about the month Sheldon spent grinding up insects and mixing them into Leonard's food?

Sheldon: Wh - exCUUse me, that was not a betrayal, that was an experiment to determine at what concentration food starts tasting... mothy.

Leonard: You put moths in my food?!

Sheldon: ...For science.
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I felt it myself, the glitter of nuclear weapons. It is irresistible if you come to them as a scientist. To feel it’s there in your hands. To release the energy that fuels the stars. To let it do your bidding. And to perform these miracles, to lift a million tons of rock into the sky, it is something that gives people an illusion of illimitable power, and it is in some ways responsible for all our troubles, I would say, this what you might call "technical arrogance" that overcomes people when they see what they can do with their minds.
—Nuclear physicist and mathematician Freeman Dyson explains how it feels
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Science isn't about why, it's about why not? Why is so much of our science dangerous? Why not marry safe science if you love it so much? In fact, why not invent a special safety door that won't hit you on the butt on the way out, because you are fired! Not you, test subject, you're doing fine. Yes, you. Box. Your stuff. Out the front door. Parking lot. Car. Goodbye.
—Aperture Science CEO Cave Johnson, Portal 2
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I'll be honest, we're throwing Science at the wall here to see what sticks. No idea what it'll do.
Cave Johnson again, Portal 2
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That's because to him, the fruits of his own research are everything, far more important than the Organization or the battle in our own country.
Rimuto, Claymore
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You would risk an apocalypse out of sheer curiosity!?
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Sharp stopped walking and turned to the scientist. "So what good is this information to us?" he asked with some annoyance.

"Well..." Lee paused, "as pure science it’s fascinating" he said. "Not everything we do should have a military application surely?" he asked then looked awkward.
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The one thing you have to learn with science is that if you stop to ask yourself if you should do something, you've already lost faith in thinking that you can do it.
Dr. Shelly Percey, City of Villains
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Then we proceed, blindly, in the noble pursuit of science and knowledge.
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Being a scientist means never having to say you're sorry.
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I defeated a racoon! SCIENCE!
M.O.D.O.K.'s win quote against Rocket Raccoon, Marvel vs. Capcom 3
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