Four-Philosophy Ensemble/Video Games

Dragon Age II:

Cynic	Fenris	traumatized, bitter and snarky warrior
Realists	Varric & Aveline	the former as savvy, level-headed merchant prince; the latter as protector and group conscience
Optimists	Merrill & Sebastian	the former sweet and naive, wanting to help her people; the latter deeply religious
Conflicted	Hawke	Your character oneself as a Sad Clown who tries to maintain the peace in Kirkwall and amongst the companions, but often lets desire for stability prevent him/her from being more proactive.
Apathetic	Isabela	flighty hedonist

Anders straddles the line between Cynic and Idealist, being a Well-Intentioned Extremist who combines self-sacrificing loyalty to his ideals with hostility and ruthlessness.

Ever 17 female cast:

Apathetics	Cynic	Realist	Optimist
Sara & Coco	Tsugumi	Sora	Player Character

Everworld:

Apathetic	Cynic	Realist	Optimist	Conflicted
Senna (somewhat)	Jalil	April	David	Christopher

All of the opposing and antithetical factions in Fallout 4:

Cynic	The Institute	Believing it is futile to allow the Commonwealth to continue existing and want to start anew in a new society underground. However, the same people they claim to want to help fear them due to many of their own actions. To them, the Synth is Just a Machine.
Realist	Brotherhood of Steel	Ten years after the war with the Enclave, the original teachings of Elder Lyons have been lost since his death and the death of his daughter, Sarah Lyons. Arthur Maxson is in charge and wants to try and expand into the Commonwealth to oppose the Institute. To them, Synths are abominations against technology and to be detroyed down to the last.
Optimist	The Minutemen	Their original goal was to protect settlements out of good will, but they were nearly wiped out after a string of bad luck. They can make a comeback, and they are even more idealistic than ever, despite all the crud they've been dragged through. They're flexible on policy when it comes to Synths.
Apathetic	The Railroad	Views the Synths as living, thinking beings worthy of respect, and wants to liberate all Synths from the Institute. The problem is that this is their only goal, and they don't really care about anyone else in the Commonwealth.

And then, your companions:

Cynics	Cait	X6-88	Old Longfellow
Realists	Piper	Deacon	Hancock
Optimists	Preston	Curie	Nick Valentine
Conflicted	Paladin Danse	Strong & Ada	Porter Gage
Apathetics	Dogmeat	Codsworth	MacCready

The Turks from Final Fantasy VII fall into this category:

Apathetic	Cynic	Realist	Optimist
Reno	Tseng	Rude	Elena

Final Fantasy XIII:

Apathetic	Cynic	Realist	Optimist	Conflicted
Fang	Hope	Lightning	Snow	Vanille & Sazh

Gears of War 2:

Apathetic	Cynic	Realist	Optimists
Dizzy	Baird	Marcus	Don & Cole

The two main protagonists of Guilty Gear and Blaz Blue fit this trope:

Apathetic	Cynic	Realist	Optimist
Ragna the Bloodedge	Jin Kisaragi	Sol Badguy	Ky Kiske

Half-Life 2:

Apathetic	Cynic	Realist	Optimist
Dr. Mossman	Barney Calhoun	Dr. Kleiner	Alyx Vance

The first Knights of the Old Republic:

Apathetic	Cynic	Realist	Optimist	Conflicted
Canderous	Carth	Juhani	Mission (very much)	Bastila

Canderous counts in being a Mandalorian on a boatload of Jedi and Republic sympathizers, and has nothing better to do.

Left 4 Dead:

Apathetic	Cynic	Realist	Optimist
zombie-knowledgeable Zoey	Francis who hates everything	Bill the experienced	Hopeful Louis

Left 4 Dead 2:

The Legend of Dragoon:

Apathetic	Cynic	Realist	Optimist	Conflicted
Haschel, when he joins	Rose	Dart	Lavitz	Shana

This setup holds from the time when Rose joins all the way until Dragoon's It Was His Sled moment happens, where it transitions into a proper Five-Man Band.

Mega Man X: The Maverick Hunters, Commander, Mission Operator, and mechanic X5-X8:

Cynic	Zero	the Anti-Hero, Unfettered, with a killer-instinct
Realist	Signas	the mediator who always admires X's pacifism, but always realistic about the need to fight for peace and justice.
Optimist	Douglas (X5-6); Axl (X7-8)	the former as idealistic and confident, although this is not expanded upon; the latter seeks to rectify the wrongs of his former affiliation and believes he can take on the world
Conflicted	X	Willing to fight for peace and justice at first, but a pacifist paranoid of breaking the first robotics rule (not to harm a human), then temporarily retires and reluctant to let Axl become a hunter
Apathetic	Alia	the Mission Operator, Computer Specialist and Navigator in the series, less in-story involvement otherwise

Counting only the three Hunters as far as their murder-restraint ethics, X's honor code for taking the high road shows his Optimist side, contrasting Zero (Cynic), in which case Trigger-Happy Axl is the middle-ground (Realist) between the two.

Mega Man Zero — Counting the 1st game's Four Guardians and the four bosses in the 2nd's "Chase Elpizo" mission (three of the same, totaling five):

Cynic	Phantom	Out of fierce loyalty to Master X (a copy, rather), seldom thinks about anything besides antipathy toward "Mavericks" and, therefore, resorts easily to drastic Anti-Hero measures of explosive-detonation, for instance the factory in the first game.
Realist	Fefnir	Mostly just a competitive Blood Knight into defense as a Guardian for the fun of it, a lot like Leviathan, but a more encouraging character.
Optimist	Burble Hekelot	He does his job of protecting a Neo Arcadian forest very faithfully; driven least by selfish, prideful motives and farthest from Anti-Hero of all of them, besides Harpuia.
Conflicted	Harpuia	Sense of honor and most merciful of all like an Optimist (and does Guardian tasks for only the right reasons, contrasting Leviathan), yet still not easily trusting of anyone on the opposite side of the conflict; often pondering whether to lean more to Cynic or Optimist in many situations.
Apathetic	Leviathan	Preoccupied with her pride as a Worthy Opponent to any "Maverick" and not being condescended upon for being a female reploid; Sociopathic Hero retiring hundreds of Resistance soldiers in the second game out of sheer boredom.

Metroid Prime 3: Corruption:

Apathetic	Cynic	Realist	Optimist
Ghor	Rundas	Samus	Gandrayda

The boys in Nameless:

Apathetic	Cynic	Realist	Optimist	Conflicted
Yuri	Lance	Tei	Red	Yeonho

Yuri does care but either expects things to work themselves out or acts without consulting the others.

You and your many rivals in Pokémon Black and White (before Character Development):

Apathetic	Cynic	Realist	Optimist
N	Cheren	Hilbert/Hilda	Bianca

The crash survivors from Remember 11:

Apathetic	Cynic	Realist	Optimist
Kuni	Mayuzumi	Yomogi	Kokoro

Sly Cooper:

Cynic	Realist	Optimist	Conflicted
Bentley	Sly	Murray	Carmelita

Sly has a lot of Apathetic aspects to him as well.

The Star Fox team:

Cynic	Realist	Optimist	Conflicted
Falco	Fox	Slippy	Krystal

In earlier games, Fox was more the Conflicted while Peppy filled the Realist spot before Krystal replaced him.

Tales of the Abyss:

Cynics	Realists	Optimist	Conflicted
Jade & Anise	Guy & Tear	Natalia	Luke

This actually becomes a gameplay mechanism in This War of Mine when it comes to emotion levels; the Optimist is much more eligible for mood swings than the Cynic, and the more emotional characters are better at curing depression.

Cynics	Roman	Bruno	Emilia
Realists	Marco	Pavle	Katia
Optimists	Zlata	Boris	Cveta
Apathetics	Marin	Arica	Anton

The playable characters of the Touhou project:

Apathetics	Cynic	Realist	Optimist
Sakuya & Youmu (taking turns)	Reimu	Marisa	Sanae