Best known for her work on The Simpsons, Nancy Cartwright has been doing cartoon voices since Hanna-Barbera's version of Richie Rich in the early 1980s. She is also an animation producer, responsible for NASCAR.com's Web Animation series The Kellys. She has adapted her book, My Life as a 10-Year-Old Boy, into an audiobook and a one-woman stage show.
Cartwright has also appeared in live action, including Joe Dante's segment of Twilight Zone the Movie and the Made for TV Movie Marian Rose White, and the American Godzilla movie (which also had Hank Azaria and Harry Shearer of The Simpsons). She even was a celebrity guest on Tom Bergeron's Hollywood Squares and Donny Osmond's Pyramid. Outside show business, Cartwright is a prominent member of the Church of Scientology.
Cartwright has done character voices for the following animated series:
- Richie Rich (Hanna-Barbera's version)
- Shirt Tales (season 2 only, as Kip Kangaroo)
- The Snorks
- Popeye and Son
- Saturday Supercade (season 2 only, in "Space Ace" segments)
- Galaxy High
- Animaniacs (Mindy, additional voices)
- The Simpsons (Bart Simpson, Ralph Wiggum, Nelson Muntz, Kearney [the bully who looks like a teenager, but isn't], Todd Flanders, and any one-shot boy characters. Cartwright also provides vocal effects [mostly cooing, laughing and crying] for Maggie Simpson and was the replacement voice for Elizabeth Taylor when the season 13 episode of The Simpsons showed a clip from season 4's "Lisa's First Word", where Maggie finally says her first word — "Daddy" — after Homer wishes that she never speak)
- Rugrats (Chuckie season 8 onward)
- Goof Troop (Pistol Pete)
- The Critic (Margo Sherman)
- Kim Possible (Rufus)
- The Replacements (Todd Daring)
- Mike Lu and Og (Lu)