Dawson Casting: 28-year-old Andrew Garfield & 23-year-old Emma Stone as the teenaged Peter & Gwen.
Fake Nationality: American-born Englishman Andrew Garfield as Peter Parker. Possibly Rhys Ifans as Dr. Curt Connors. He's revealed to have some kind of accent in one trailer.
Shout-Out: Watch the first trailer and try to deny that the first person sequence of Spidey running along rooftops doesn't look like it belongs in Mirror's Edge.
Shown Their Work: Van Adder isn't an original creation for the film, he's a very obscure Spider-Man villain called the Proto-Goblin. How obscure? The character's sole appearance was in an issue of Peter Parker: Spider-Man written in 1999, as someone Norman Osborn tested the Goblin Serum on before he used it himself.
What Could Have Been: The script for Spider-Man 4 which caused Raimi to leave the series and Columbia Pictures opt to simply go for a Continuity Reboot rather than find a new director and cast to continue Raimi's story.